https://www.youtube.com/user/GoogleWebmasterHelp
https://www.youtube.com/user/GoogleDevelopers
https://www.youtube.com/user/GoogleTalksArchive
https://www.youtube.com/user/AtGoogleTalks
https://www.youtube.com/user/GoogleVentures
Tech
https://www.youtube.com/user/NextDayVideo
https://www.youtube.com/user/MarakanaTechTV
https://www.youtube.com/user/MIT
https://www.youtube.com/tekbreakfast
Gadgets
https://www.youtube.com/user/kurtjmac
https://www.youtube.com/user/engineerguyvideo
Business / StartUps
https://www.youtube.com/user/EntrepreneurOnline
https://www.youtube.com/user/EverySteveJobsVideo
https://www.youtube.com/user/PandoDaily
https://www.youtube.com/user/princetonstartuptv
https://www.youtube.com/user/StartupBootcamp
https://www.youtube.com/user/confreaks
Programming
https://www.youtube.com/user/OreillyMedia
https://www.youtube.com/user/Froblyx– Game design and development
https://www.youtube.com/user/FacebookDevelopers
https://www.youtube.com/user/khanacademy
Random
https://www.youtube.com/user/Vsauce — IMHO the best youtube channel in existence. Every video is a rabbit hole of interesting questions and tangents with fantastic presentation and weirdly uplifting closing points.
https://www.youtube.com/user/pbsideachannel — Smart thought provoking videos that use internet memes, gaming, anime, and such as the launch off points.
https://www.youtube.com/user/1veritasium — Well presented science videos with a focus on the joy of learning.
https://www.youtube.com/user/destinws2
https://www.youtube.com/user/gluse –Man riding up elevators in different building
https://www.youtube.com/user/SMOKERSOFCIGARSPIPES — 6300+ man smoking cigars/tobacco pipes and grumbling